All three members of ESPN are picking the 49ers as well. ESPN's Football Power Index simulation model has the 49ers winning this game 61.2% of the time and doing so by an average of 4.3 points. The Indianapolis Colts are at home in Week 16 for a Monday Night matchup with the San Francisco 49ers.

The expected and wise move from the San Francisco 49ers has come to fruition. Kyle Shanahan announced on Saturday at his final Week 16 press conference that the

Colts coach Shane Steichen said starting DT DeForest Buckner will make his return Monday night vs the 49ers after missing 5 games with a neck injury.

The Indianapolis Colts released their final injury report ahead of a crucial Monday Night game against the San Francisco 49ers. Four players have been ruled out, while two are questionable. Among those who are questionable are DeForest Buckner (neck) and Bernhard Raimann (elbow).

Declining in any facet is the last thing the San Francisco 49ers can afford right now. The playoffs are steadily approaching. They need to be as strong as possi

Sports analyst gives a bold prediction about Philip Rivers before game vs 49ers originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here.

San Francisco would have a better chance at the No. 1 seed in the NFC playoffs if Seattle can pull off the victory at home.

The Indianapolis Colts are currently riding a four-game losing streak. It makes their matchup perfect timing for the San Francisco 49ers. However, the Colts sti