The human genome contains approximately 1,600 types of transcription factors responsible for regulating gene activity across ...

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

Clock genes are a set of genes known to contribute to the regulation of the human body's internal 24-hour cycle, also known as the circadian rhythm. One of these genes is the so-called CLOCK gene, a ...

Scientists identified 473 human genes that act as genetic “on/off switches,” shaping disease risk through tissue-specific or universal patterns regulated by DNA changes and hormones. Study: ...

David Liu and Richard Merkin of the Broad Institute of MIT and Harvard, along with Columbia professor Sam Sternberg, have developed a new, targeted means of inserting entire genes into human DNA ...

Scientists have discovered that a gene called MUC19, inherited from Denisovans through ancient interbreeding, may have played a vital role in helping Indigenous ancestors adapt as they migrated into ...

Researchers at University of Tsukuba have comprehensively analyzed genomic binding data of transcription factors (proteins that regulate gene expression) in humans, revealing a substantial amount of ...