Researchers at the Francis Crick Institute studying male mice engineered with different Y chromosome deletions have uncovered which genes on the mouse Y chromosome regulate the development of sperm ...

Humans have 23 pairs of chromosomes, including a pair of sex chromosomes (typically XX for females, and XY for males). Chromosomes contain hundreds to thousands of genes, which are sections of DNA ...

In 2002, evolutionary biologist Jenny Graves shared a controversial calculation. The human Y chromosome, she wrote two years later in a commentary, "is running out of time." The male-determining sex ...

Rather than leading to the disappearance of males, Y chromosome decline could trigger new sex determining systems . Similar shifts have already occurred in other mammals. The article suggests that ...

Scientists remain divided over whether the human Y chromosome will eventually vanish. But clinicians say the real concern ...

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some men don't ...

University of Virginia School of Medicine researchers have discovered a gene on the Y chromosome that contributes to the greater incidence of heart failure in men. Y chromosome loss in men occurs ...

Researchers have shed new light on how a type of heart valve disease -- aortic valve stenosis -- progresses differently in males and females. A study led by bioengineers at the University of ...

Maternal genetics have an outsized role to play, as they shape body's response to stress, ability to fight with infections ...

The silencing of the one X chromosome in XX cells is mediated by XIST, a long noncoding RNA that is randomly transcribed from only one X early in development. It coats the DNA and shuts down gene ...