Figure 1: Ligation probe oligonucleotides used in the study. Ligation reaction products were analyzed by gel electrophoresis in a fluorescence sequencing instrument, to identify and quantify the five ...
Complex DNA sequences are difficult to detect and profile, but are important contributors to human health and disease. Existing hybridization probes lack the capability to selectively bind and enrich ...
SNIPRs (Single-Nucleotide-Specific Programmable Riboregulators) can identify any RNA sequence based on a single nucleotide difference. [Shireen Dooling, Biodesign Institute, ASU] SNIPRs, easy-to-build ...