Oligonucleotide microarray (DNA chip)–based hybridization analysis is a promising new technology which potentially allows rapid and cost–effective screens for all possible mutations and sequence ...

Figure 1: Ligation probe oligonucleotides used in the study. Ligation reaction products were analyzed by gel electrophoresis in a fluorescence sequencing instrument, to identify and quantify the five ...

We compared the applicability of an enhanced chemiluminescent (ECL) method for using gene probes with that of radioactive probes to identify enterotoxigenic Escherichia coli (ETEC) in stools of ...

Therapeutic oligonucleotides act on different stages of pathological gene expression. Standard schematic of oligonucleotide activities in pathogenesis disease progression. Decoys bind to transcription ...

The ability to label nucleic acids with a variety of tagged molecules has led to astonishing advances in molecular biology. Labeled DNA, RNA, and oligonucleotide probes have made possible techniques ...

BHQplus Probes form more stable probe-target duplexes, enabling shorter oligonucleotide designs. Shorter oligos offer high specificity and better detection of difficult targets, such as AT-rich ...

About nonradioactive nucleic acid detection -- Isolation of DNA from plants -- Isolation of high-molecular-weight DNA from animal cells -- Restriction enzyme digestion, gel electrophoresis and vacuum ...

Use of Adapter Blocking Oligos for In-Solution Hybridization Improves Target Capture Performance In-solution hybridization (target capture) has been used since the early days of next-generation ...

High-resolution melting has proven to be a highly sensitive method for mutation discovery. PCR is performed in the presence of the double-strand DNA binding dye LCGreen® Plus. Samples are then ...

PCR has fundamentally changed molecular biology, offering a rapid means to amplify minute quantities of DNA. Real-time quantitative PCR (Q-PCR) techniques are designed to facilitate accurate ...