Flt4 plays a key role in promoting tumor metastasis by stimulating solid tumor lymphangiogenesis. In this study, mouse Flt4 (mFlt4) was displayed on T4 phage in order to explore the feasibility of ...

Venigalla B. Rao, PhD, has been studying bacteriophages for more than four decades, mostly in small laboratories with limited personnel and funding. But having a mere eight-person lab (four post-docs, ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, No. 35 (September 1, 2015), pp. E4919-E4928 (10 pages) The first stages of productive bacteriophage ...

Aims: Novel anticancer strategies have employed bacteriophages as drug carriers and display platforms for anticancer agents; however, bacteriophage-based platforms maintain their natural antibacterial ...

This is a preview. Log in through your library . Abstract The synthesis of deoxynucleotide kinase (EC 2.7.4.2) in vitro by a preparation consisting of T4 bacteriophage DNA and a cell-free extract of ...

Bacteriophages are viruses that infect bacteria. Have you ever wondered how these guys find their bacterial “prey”? Investigators at San Diego State University demonstrated that “subdiffusive motion” ...

A team of scientists from the United States has recently developed a bioengineered bacteriophage T4 nanoparticle structure using CRISPR technology that can be used as a universal platform to produce ...

Atomic structural model of bacteriophage T4 in UCSF Chimera software using pdbs of the individual proteins. Credit: Dr. Victor Padilla-Sanchez, PhD, CC BY-SA 4.0 Atomic structural model of ...

In a recent study published in the journal Nature Communications, researchers present a method for constructing artificial viral vectors (AVVs) using the established structural components of ...

Phage interactions with bacteria are well known, and interactions between bacteria and their mammalian host can lead to a range of symbioses. However, the impact of bacteriophages on mammalian ...

“Mammalian cells actively engulf and traffic phages, so it’s important to understand the potential responses and impacts even if they are moderate to mild,” said Barr. To investigate the downstream ...