New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their failures may drive disease.
This week in Science, Michael K. Rosen and 10 other members of a large collaboration at the Marine Biological Laboratory, the Chromatin Consortium, propose a long-awaited model for how the properties ...
There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...
A team of researchers led by HHMI Investigator Michael Rosen has captured the most detailed images yet of the molecules in chromatin condensates — droplet-like structures of compacted DNA.
AZoLifeSciences on MSN
Researchers capture the most detailed images of molecules in chromatin condensates
A team of researchers led by HHMI Investigator Michael Rosen has captured the most detailed images yet of the molecules in ...
Interesting Engineering on MSN
Scientists capture the most detailed 3D views yet of DNA droplets that organize cells
Cr yo-ET captured dozens of projection images of each slice from different angles. Computational processing then stitched those projections into detailed 3D views of the condensates and their ...
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Chromatin accessibility maps reveal how stem cells drive myelodysplastic syndrome progression
Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...
In 1995, two papers reported long-sought proof of an exotic state of matter — with applications in fields as diverse as quantum computing and cosmology. Read the paper: Observation of Bose-Einstein ...
(Alamy/PA) (Condensation on your windows can be a result of cold weather, but can also be a sign that it's time to replace you windows.) A UK cold spell almost always triggers the same question for ...
The developmental period is a critical window during which environmental cues interact with the genome to shape lifelong trajectories of health and disease.
Winter has scarcely started, yet numerous households across Britain may have already spotted the warning signs of dampness: steamed-up windows, musty odours and even black mould appearing in certain ...
Persistent contacts between Climp63 and microtubules cause mitotic defects and nuclear fragmentation
This important study reveals that mitotic release of an ER-microtubule tether is critical for normal mitotic progression. Manipulating CLIMP63 phosphorylation, the authors provide convincing evidence ...
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