5 days ago · Build guides for Vayne on MOBAFire. Learn what runes and items make the best Vayne build in League of Legends (LoL).

Vayne build with the highest winrate runes and items in every role. U.GG analyzes millions of LoL matches to give you the best LoL champion build. Patch 15.24

Get the best Vayne builds, based on analysis of 10000+ matches in all regions and ranks. Climb in patch 25.24 with Vayne builds provided by Mobalytics!

Vayne 25.24 Build. Find the best runes, items, skill order, counters, and more in our statistical Vayne Build for LoL Patch 25.24. Updated Daily.

Vayne Build with the highest win rate. Runes, items, and skill build in patch 15.24. Vayne build recommendations and guides.

Top builds, runes, skill orders for Vayne based on the millions of matches we analyze daily. Also includes as well as champion stats, popularity, winrate, rankings for this champion

Read our Vayne guide, created by the high ELO players at Mobalytics. Everything you need to know about Vayne : tips and tricks, game plan, power spikes & more!

If you want to learn how to play Vayne on your matches, keep in mind that this champion is mechanically advanced to play in LoL. This Vayne guide will give you also an understanding on how to beat Vayne.

5 days ago · Find the best meta build guides for Vayne in 2025, Season 3 Patch 25.24. The MOBAFire community offers quality Vayne builds and knowledge to improve your performance and win rate.

The most detailed and best Vayne Build, Runes & Counters Guide for bottom Vayne on LoL Patch 15.24 are found on LoLalytics.